A Brief History of Hannibal Regional Healthcare System

At the turn of the twentieth century, there was no hospital to serve citizens of northeast Missouri. With the opening of Levering Hospital on February 2, 1903, the need for hospital care was met and the first part of what would become Hannibal Regional was created. More than a century later, Hannibal Regional continues this commitment to being the leader in healthcare, furthering their mission of guiding the community to better health and shaping the future of healthcare for its residents.

Prior to the opening of Levering Hospital, the sick were cared for in the home, and any surgery needed was performed there or in a doctor’s office. In 1901, Aaron R. Levering, President of the Farmers and Merchants Bank of Hannibal, and his wife, Eleanor M. Levering, recognized the need for a hospital to serve the community. The Leverings dedicated land and donated funds for the construction of a hospital in Hannibal and it would be called “Levering Hospital”.

When Levering Hospital opened its doors it was the first erected hospital in northeast Missouri and contained twenty-six patient beds. Throughout its history, Levering Hospital received the support of many other contributors in the form of time, talent and funds. Over the years citizens, religious and civil organizations, and the Levering Hospital Auxiliary generously and unselfishly gave their energy and money to the hospital, truly making it a “Community Partnership.”

A few years later, St. Elizabeth’s Hospital was organized and founded by the Sisters of St. Francis of Maryville, MO. The Reverend Mother, M. Augustine, founder of the Sisters of St. Francis, was also the founder of St. Elizabeth’s Hospital. The land for the hospital was purchased in the fall of 1913, and the hospital was completed and received its first patients in the summer of 1915.

Eight young, energetic nursing sisters were sent to Hannibal to operate the hospital. These sisters, with the help of some local citizens, readied the newly constructed hospital to serve the community. This hospital was located on Virginia Street and had thirty-five patient beds.

In July 1987, after many months of discussion and planning, the Board of Directors for both Levering Hospital and St. Elizabeth Hospital entered into an affiliation agreement to explore the consolidation of both hospitals. In 1988, the two facilities merged, forming Hannibal Regional Hospital.

Hannibal Regional has been an independent provider of health care for the past 115 years and has been at its current location for more than 25 years. Expanding beyond hospital services, Hannibal Regional now has over 1,400 team members serving 14 counties, offices located in 12 communities, 85 providers and 21 specialties, Hannibal Regional continues to lead the way in providing access to exceptional healthcare and guiding the residents of Northeast Missouri to BETTER.




Cornerstone of Levering Hospital is Created

Cornerstone of Levering Hospital is laid on June 19, 1902 making it the first building to be erected as a hospital in Missouri.


nurses lined up in front of the hospital

First Patients Received

First patients are received at Levering Hospital's original 26 bed facility.

Levering Auxillary

Levering Auxillary is established.

First Nursing Class Graduates

Levering Hospital's School of Nursing graduates their first class.


Levering hospital

Residence Hall for Nurses Founded

A.R. Levering Family funds construction of residence hall for Levering Hospital nurses.

Levering Hospital Opens

First patients are received at Levering Hospital's original 26 bed facility.



St. Elizabeth's land acquired

The Sisters of St. Francis of Maryville, Missouri purchase a 220 acre tract of land for future site of St. Elizabeth's Hospital


St. Elizabeth Hospital

St. Elizabeth's Hospital is Complete

First patients are received at St. Elizabeth's original 35 bed facility.


St. Elizabeth Auxillary

St. Elizabeth Auxillary is established



Addition to Levering Hospital complete

The addition to Levering Hospital is completed. Gift of business man Wilson B. Pettibone



St. Elizabeth Hospital Chapel

St. Elizabeth Hospital's Chapel and Sister's residence is completed


Levering Hospital Receives Another Addition

Levering Hospital receives another addition Dr. J.W. Hardesty applied for another addition to Levering Hospital to be built under the Federal Works Project administration. This addition provided 42 rooms, bringing the total bed capacity to 116.


Levering Obstetrical department complete

The new levering Hospital Obstetrical department and 3rd floor nursery is completed.



St. Elizabeth groundbreaking

St. Elizabeth's groundbreaking for new addition that will more than double the hospital's size.



Levering addition completed

The final Levering large addition and renovation completed making it a 150 patient hospital.


Hannibal School of Practical Nursing

Hannibal Public School of Practical Nursing opens and is later incorporated into the Hannibal Public School System.



St. Elizabeth's West Wing Completed

The six-level west wing of St. Elizabeth's is completed.



Hannibal Regional Healthcare System is formed

Levering Hospital works toward consolidation with St. Elizabeth's Hospital. Boards at Levering and St. Elizabeth's enter affiliation agreement.


Consolidation of Acute Care Services

Hannibal hospitals consolidate Acute Care Services at the former St. Elizabeth's facility.



Approval of Cancer Program

Hannibal Regional Hospital's Cancer Program approved by American College of Surgeons


LaGrange, MO Clinic Opens

Hannibal Regional Hospital opens its first primary care clinic in LaGrange, MO


Hannibal Regional Hospital Opens in New Building

Hannibal Regional Hospital moves to a state-of-the-art new building next to US 36.


Primary Care Clinics

Center and Shelbina Primary Care Clinics open


Primary Care Clinic

Canton Primary Care Clinic opens


Primary Care Clinics

Monroe City and LaBelle Primary Care Clinics open


Primary Care Clinics

Vandalia Primary Care Clinic opens


Open MRI

Open MRI was one of the many technological innovations introduced to the Tri-state area in 1998

Outpatient Rehabilitation

Hannibal Regional Hospital Physical Therapy and Hand Center opens



Hannibal Children's Center opens

Hannibal Children's Center provides parents with the ability to work with the comfort of knowing their children are safe and secure in an environment which is developmentally supportive of their individual needs.



Hannibal Regional Hospital's newly expanded Sleep Diagnostics Laboratory opens, a Home Health Agency is opens in in Hull, Illinois, there is a Primary Care Clinic opened in Palmyra, Missouri and the Diabetes Center receives accreditation.


Primary Care Clinic

Bowling Green Primary Care Clinic is opened

PET Scanning

Positron emission Tomography (PET) is added to the Radiology department


James E. Cary Cancer Center

Hannibal Regional Hospital and Hannibal Clinic develop the area's first cancer center.


New ES Expansion Complete

Hannibal Regional Hospital opens a brand new state of the art emergency services department with 18 rooms.


Department dedications

Hannibal Regional Hospital dedicated the new Chris Coons Women's Care Center and the Alfred F. Nagy Emergency Department.


Hannibal Regional Medical Building Opens

Hannibal Regional Medical Group completes it's 3-stroy medical office building and begins serving patients.



Express Care Walmart

Hannibal, MO "Express Care opens inside Hannibal's Walmart Supercenter"


Acquisition of Pike Medical Group

Added clinics in Bowling Green and Louisiana.


Inpatient Rehabilitation Unit Opens

The Inpatient Rehabilitation Unit is a distinctly separate nursing unit and offers dining, activity, and therapy space. Patients in the Inpatient Rehabilitation Unit receive a minimum of three hours of therapy a day or 15 hours of therapy over a seven day period.


CFM joins Hannibal Regional

Kirksville Chamber of Commerce and Complete Family Medicine hosted a ribbon cutting to celebrate CFM joining Hannibal Regional.

Northeast Missouri Imaging Associates and Hannibal Medical Services join our team

Welcome, Northeast Missouri Imaging Associates and Hannibal Medical Services to our team!

Groundbreaking for Expansion Construction

The groundbreaking celebrated the beginning of the construction on the expansion of the Hannibal Regional Medical Group building.


Bowling Green Ribbon Cutting

The new clinic in Bowling Green open house and ribbon cutting.


Surgery Suite Expansion

Six state-of-the-art surgery suites opened offering the latest technology including a 4k fluorescence surgical camera from Stryker and a daVinci surgical system.


Hannibal Regional Medical Building Expansion

The Hannibal Regional Medical Building expanded its footprint to offer more specialties and providers to the community.



Hospital Entrance Expansion

Construction on the updated hospital entrance is complete.  Included in the hospital entrance expansion is private registration bays, relocation of the hospital laboratory entrance, a larger Courtyard Cafe, new surgery waiting room and the addition of a conference room.


Hospice of Northeast Missouri

On January 1, 2022, Hospice of Northeast Missouri’s Board of Directors made the decision to partner with Hannibal Regional Healthcare System to assist in providing expanded resources and to ensure continued quality end of life care throughout Northeast Missouri.  Hospice of Northeast Missouri is a volunteer organization formed to address the community need for end-of-life care.


Open Heart Surgery Program Launched

On November 14, 2023, the first Open Heart surgery was performed at Hannibal Regional by Dr. Jose Torres.  


CFM Opens New Location

Complete Family Medicine opens a new location in Paris, MO

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